中国科学院重庆绿色智能技术研究院机构知识库

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	Recent Studies on the Application of Patch-Clamp Technique in Cellular Electrophysiology
	Jia, Wei-Jiao1,2; Dai, Guang-Bin2,3; Geng, Guo-Shuai2,3; Yang, Zhong-Bo2; Tang, Ming-Jie2; Xiu, Peng4; Zhang, Feng1; Wang, Hua-Bin2,5
	2018
摘要	Cellular physiological properties are closely related to the biological, chemical and physical properties of cells. Patch-clamp technique is useful in the investigation of cellular physiological functions by measuring electric current of individual cells or ion channels in cell. Patch-clamp techniques including its fundamental principle, cellular electrical signal measurement and data analysis are reviewed. Recent progresses of patch-clamp technique in the application of investigating chemical and biological mechanisms of cellular electrophysiology are summarized. Moreover, new techniques developed by combining the patch-clamp technique with other instruments are discussed, and their application in cell electrophysiological study is reviewed. Finally, the patch-clamp technology is summarized and its future application is discussed. © 2018, Editorial Board of "Journal of Chemical Engineering of Chinese Universities". All right reserved.
DOI	10.3969/j.issn.1003-9015.2018.04.004
发表期刊	Gao Xiao Hua Xue Gong Cheng Xue Bao/Journal of Chemical Engineering of Chinese Universities
ISSN	10039015
卷号	32期号:4页码:767-778
收录类别	EI
语种	中文